genej101,
Well, nothing is 100% in the software world especially on the security side. PC-Doctor is low level hardware diagnostic software, maybe this is what Comodo thinks is "possibly dangerous". This is odd since PC-Doctor is installed by manufacturers on literally millions of systems. I would think they would have seen this before in testing. Maybe an email to Comodo support is in order.
I would put pcdrui.exe on the ignore list and move on.
-Fred